Mewtwo is card #10 of 130 in Base Set 2 (2000), a Rare Holo illustrated by Ken Sugimori. At about $130 it is the #3 most valuable card in the set. In a Base Set 2 booster it turns up about once every 59 packs. It is one of 89 Mewtwo cards printed so far.
1999Base Set
2000Gym Challenge
2003Ruby & Sapphire
2006Holon Phantoms
2009Pokémon Rumble
2015BREAKthrough
2019Unified Minds
2023Crown Zenith

















See the full Base Set 2 card list
An ungraded Mewtwo from Base Set 2 sells for about $130. A PSA 10 is worth more, roughly $1,687 by our estimate, and a PSA 9 around $519.
It is a Rare Holo, and it shows up about once every 59 Base Set 2 packs.
Ken Sugimori drew the art for this card.
Yes, as a digital simulator. Holobrook lets you open Base Set 2 booster packs in your browser with the set's real pull rates and keep what you pull in a digital binder. No real cards, nothing to buy.